Irritable bowel syndrome (IBS) is a common condition characterized by abdominal discomfort associated with altered bowel movements and is currently diagnosed according to the new Rome IV criteria.
Recent research has shown that many symptoms of IBS are related to hypersensitivity of the nerves found in the wall of the gastrointestinal tract. These nerves are distinct from those in your spinal cord and brain. For some people, IBS may arise from how the gut nerves communicate with the brain, or how the brain processes that information.
In Western countries, IBS seems to affect women twice as often as men. IBS is very common, occurring in up to 15 percent of the United States population. Most people with IBS develop their first symptoms before the age of 40, with many patients recalling the onset of symptoms during childhood or young adulthood. There appears to be a familial component, as many IBS patients report having a family member with similar symptoms. Less commonly, the symptoms of IBS develop after a severe intestinal infection; this is called post-infectious IBS.
It is important to note that IBS is very different than the similarly named disease inflammatory bowel disease (IBD).
There are four subcategories of IBS, each with equal prevalence:
Mostly diarrhea and abdominal discomfort (IBS-D).
Mostly constipation and abdominal discomfort (IBS-C).
Alternating loose stools and constipation with abdominal discomfort (IBS-mixed).
Undefined subtype (IBS-U) — symptoms vary.